Leslie shaw
prof University of Pennsylvania
Seminars
Thursday 9th October 2025
9:00 Defining Context of Use to Anchor Biomarker Relevance & Streamline the R&D Pipeline
- Determining Context of Use: Diagnostic, prognostic, predictive and pharmacodynamic
- Assay validation across research, development, and clinical stages
- When is a biomarker meaningful enough to replace or complement clinical outcomes?
- From correlation to mechanistic specificity: Tracking vs. proxy biomarkers
