Evaluating the Diagnostic Activity of Alpha Synuclein PET Tracer in PD, DLB & MSA for Earlier Diagnosis & Treatment
Time: 11:30 am
day: Conference Day Two
Details:
- Delving into preclinical characterization with ACI-12589:
- in vivo correlations between a-syn PET and dopaminergic loss
- Mapping of ACI-12589 to a-syn fibrils
- Clinical data with ACI-12589: robust quantification from dynamic scanning with arterial blood sampling and kinetic modelling to simplified methods
- Combination of PET imaging with SAA improves diagnostic accuracy of MSA and support clinical trial design
- Next generation tracer, ACI-15916 with significantly improved target occupancy has the potential to detect synucleinopathies including Parkinson’s disease
