Nadine Tatton

Company: Critical Path Institute

Job title: Executive Director

Seminars:

9:00 P-tau217: Clinical Promise, Regulatory Hurdles & the Path to Surrogate Endpoint Status 9:00 am

Highlighted by the recent approval of the first in vivo blood test for Alzheimer’s Disease, advancements in new technologies to measure p-tau217 are at an all-time-high. Join this session for an inside look on how p-tau217 is setting the gold standard in AD diagnostics, exploring its scientific evolution, clinical impact, and regulatory breakthrough, offering a…Read more

day: Pre-Conference Workshop Day

1:30 Harmonizing Different Official Consent Frameworks for CSF & Plasma Collection to Accelerate Ethical & Compliant Clinical Trials 1:30 pm

IRB and EC quantitative, qualitative and ethical requirements to ensure patient safety and well-being A walk-through best practice for getting informed patients consent for clinical trials considering populations with cognitive impairment Overview of FDA, EMA, and MHRA roles in shaping consent standards for CSF and plasma collection Read more

day: Conference Day 2

2:00 Panel Discussion: Optimizing Imaging Endpoints, Mapping the Current Imaging Landscape & Emerging Tools in Neuroscience 2:00 pm

Review of Current Imaging Modalities: Overview of PET, MRI, fMRI, and other techniques used in neurodegenerative disease trials (e.g., AD, PD, MS, ALS) Limitations of Imaging Biomarkers in Clinical Trials: Challenges including accessibility, cost, patient burden, and limitations in sensitivity or specificity Innovations on the Horizon: Discussion of emerging imaging techniques and tools, including novel…Read more

day: Conference Day 2